In live cell chemotaxis studies the degree and direction of movement of a motile cell or organism is studied as a response to the changing concentration of a chemical substance.
Real-time chemotaxis may be studied using time-lapse confocal microscopy.
A suitable confocal microscope system includes a stage top incubator with heating plate, micromanipulation equipment, fluorescent light source and appropriate filters.
The Leica DMi is an inverted, transmitted light microscope stand for Brightfield, Integrated Modulation Contrast (IMC), Phase Contrast, Darkfield, Differential Interference Contrast (DIC) and Fluorescence applications.
The fully motorised Leica DMi offers high precision 3D image reconstruction of large specimens through a combination of its closed loop focus with 20nm positional accuracy and extended 12mm travel range.
A modular system for ease of upgrade and support, the DMi features an easy to use touch panel control which can be programmed with your personal preferences. The DMi makes tasks convenient and reproducible by automatically adjusting settings.
Illumination, parfocality, brightness and diaphragm position are automatically adjusted based on the selected contrast method, whilst the Adaptive Focus Control (AFC) constantly adjusts and maintains focus.
The PCO Edge 5.5 is an extremely compact 16 bit camera which is equipped with a scientific CMOS sensor and is ideally suited for measuring images at high resolution and high frame rates.
|Thermal stabilization (°C )||0 / +5|
|Read-out noise (e- med)||1.0|
|Resolution (pixels)||2560 x 2160 (5.5 Megapixel)|
|Dynamic range||30000 : 1|
|Exposure time (secs)||0.1 to 2|
|Maximum frame rate (fps)||30|
|Read-out modes||Rolling or global / global reset functionality|
|Sensor||Black and white sCMOS|
|Dimensions (mm)||102 x 79 x 70|
The Aurox Visionary software has been specially developed for the acquisition of live cell imaging data using the Aurox Clarity LFC unit as part of a laser free confocal microscopy system.
Designed with simplicity and ease of use at its core, the software provides a single graphical user interface, which relates device and experimental settings directly to the connected instrument hardware.
The Visionary software provides for the optimisation and control of the instrument set-up and calibration followed by the set-up and image acquisition control of the confocal microscopy experiment.
Key features of the software:
|Working Distance (mm)||0.14|
The Prior Scientific H117 motorised XY stage series is suitable for use with most new inverted microscopes and has a completely flat top for easy access.
The H117 series includes Intelligent Scanning Technology (ITS), which allows the stage to be programmed for optimum set-up and performance. ITS also allows the ProScan™ III controller to adjust for and maintain superior orthogonality and metric accuracy.
The OkoLab stage top incubator chamber creates the ideal environment for live cell imaging on the microscope stage.
Incubators are available to fit any microscope XY stage or piezo insert and all connect to Okolab temperature, gas and humidity controllers.
Aurox offer service and support contracts to cover all Aurox Clarity confocal microscopy systems.
Service contracts can be purchased in 1 year or up to 5 year intervals.
Aurox service contracts include: